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#Azathioprine Uses
Azathioprine, 6-mercaptopurine, mycophenolate mofetil - Free Sketchy Medical Lesson
Azathioprine, 6-mercaptopurine, mycophenolate mofetil - Free Sketchy Medical Lesson
sketchy.comSep 4, 2022
PharmD.Hadeel on Instagram‎: "❤️Azathioprine : هو Immunosuppressant agent، يعني دواء يقلل نشاط الجهاز المناعي، وغالبًا نستخدمه لما يكون في أمراض مناعية أو بعد زراعة أعضاء. ❤️آلية عمل Azathioprine: هو مشتق من 6-mercaptopurine (6-MP)، وبعدين يتحوّل بعد ما يدخل الجسم لمركبات نشطة أهمها 6-thioguanine nucleotides (6-TGNs). هالمركبات تدخل الـDNA أثناء انقسام الخلايا وتوقف DNA replication، خصوصًا في الخلايا سريعة الانقسام مثل خلايا الجهاز المناعي. كمان الدواء يثبّط purine synthesis، فيقل تصنيع DNA وRNA
PharmD.Hadeel on Instagram‎: "❤️Azathioprine : هو Immunosuppressant agent، يعني دواء يقلل نشاط الجهاز المناعي، وغالبًا نستخدمه لما يكون في أمراض مناعية أو بعد زراعة أعضاء. ❤️آلية عمل Azathioprine: هو مشتق من 6-mercaptopurine (6-MP)، وبعدين يتحوّل بعد ما يدخل الجسم لمركبات نشطة أهمها 6-thioguanine nucleotides (6-TGNs). هالمركبات تدخل الـDNA أثناء انقسام الخلايا وتوقف DNA replication، خصوصًا في الخلايا سريعة الانقسام مثل خلايا الجهاز المناعي. كمان الدواء يثبّط purine synthesis، فيقل تصنيع DNA وRNA
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