It is usually divided into medial and lateral regions with three bands with distinct properties and connectivity running perpendicular across the whole area. A distinguishing characteristic of the EC is …

Anatomically, the EC is a transitional cortex exhibiting features of both paleocortex and neocortex, characterized by a six-layered organization with distinct cytoarchitectonic features such as neuronal …

Aug 23, 2025 · The entorhinal cortex (plural: cortices) (a.k.a. Brodmann area 28) is located in the mesial temporal lobe and acts as the interface between the hippocampus and the neocortex.

Jun 28, 2017 · Neurons in layer II are the main source of the entorhinal projections to the dentate gyrus and fields CA2 and CA3, and neurons in layer III give rise to the entorhinal projections to CA1 and …

Entorhinal cortex is situated as an important nodal point between the neocortex and the hippocampus, with superficial layers relaying neocortical input to the hippocampus and deep layers broadcasting …

Nov 3, 2013 · Output of the hippocampal formation preferentially targets layers V and VI of the entorhinal cortex, which in turn are the origin of widespread reciprocal cortical projections and …

Aug 5, 2025 · It is divided into two main subfields: the medial entorhinal cortex (MEC) and the lateral entorhinal cortex (LEC). These subdivisions have distinct properties and connections. The entorhinal …