KEY POINTS Genitourinary syndrome of menopause (GSM) is common and can be treated with over-the-counter vaginal lubricants or supplementation with vaginal estrogen. Vaginal energy devices (such as CO2 ...

See related article at A crisis of communicable diseases is unfolding in North America, just as Canada’s health systems’ responses are being hampered by the dismantling of public health and research ...

A pregnant, primiparous 32-year-old woman at 28 weeks’ gestation presented for a routine prenatal visit. Blood work showed thrombocytopenia with platelet count of 60 (reference range 130–380) × 109/L.

Iron deficiency and iron deficiency anemia are common during pregnancy and are associated with adverse outcomes Prenatal iron deficiency occurs in more than 30% of pregnancies in Canada. 1 It has been ...

A meta-analysis of 20 000 people from the general population who were patch tested confirmed a 20% prevalence of contact allergy, with nickel being the most common allergen (11.4%). 1 Prevalence is ...

Background: Cancer surveillance data are essential to help understand where gaps exist and progress is being made in cancer control. We sought to summarize the expected impact of cancer in Canada in ...

Background: Recent data suggest an increased risk of congenital anomalies with prenatal exposure to opioid analgesics. We sought to further quantify the risk of anomalies after opioid analgesic ...

KEY POINTS The World Health Organization prioritized dietary sodium reduction and declared a “30% reduction in population sodium intakes by 2025” as 1 of 9 global targets for noncommunicable disease ...

KEY POINTS Recent data suggest that almost 10% of patients who undergo coronary artery bypass grafting (CABG) are readmitted to hospital within 30 days of surgery. Patients who lack primary care ...

Background: Rates of gestational diabetes are reported to be increasing in many jurisdictions, but the reasons for this are poorly understood. We sought to evaluate the relative contribution of ...

Background: Respiratory syncytial virus (RSV) vaccines could reduce disease burden and costs in older Canadian adults, but vaccination program cost-effectiveness is unknown. We evaluated the ...

When central venous access cannot be established delivering vasopressors via peripheral catheters is acceptable Administration of vasopressors through peripheral venous catheters has traditionally ...