BACKGROUND: Recent studies have highlighted the deleterious role of high phosphate intake in hypertension by means of ...

During aging, deterioration in cardiac structure and function leads to increased susceptibility to heart failure. The need for interventions to combat this age-related cardiac decline is becoming ...

BACKGROUND: Previous research suggests that exposures to air pollution and nonoptimal temperatures are associated with a ...

COVID-19 is characterized by dysregulated thrombosis and coagulation that can increase mortality in patients. Platelets are fast responders to pathogen presence, alerting the surrounding immune cells ...

Aortic valve (AV) sclerosis (AVS) is a form of AV disease affecting an estimated 1 in 4 people above the age of 65 in the United States. 1 An aging population and more widespread use of noninvasive ...

Values are mean±SD unless otherwise indicated. Component definitions are shown in Table S1. BMI indicates body mass index; BP, blood pressure; DASH, Dietary Approaches to Stop Hypertension; PA, ...

Not many decades ago, it was the rare patient with a functionally univentricular heart who survived to adulthood. 1 While this grim prognosis has gradually improved over the years, the diagnosis of ...

A 46-year-old woman with type 1 myotonic dystrophy (DM1) presented to the emergency department with dyspnea and palpitations.

Hypertriglyceridemia (triglycerides 200–499 mg/dL) is relatively common in the United States, whereas more severe triglyceride elevations (very high triglycerides, ≥500 mg/dL) are far less frequently ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Cardiovascular disease (CVD) is the leading cause of death in women, who have a notable increase in the risk for this disease after menopause and typically develop coronary heart disease several years ...

BACKGROUND: Desmosomal gene variants (DGVs) have been associated with a diverse spectrum of phenotypic manifestations within ...