San Francisco 49ers rookie running back Isaac Guerendo (foot, hamstring) is off the injury report and ready to roll for a ...

Who Should I Start? Who Should I Sit? Some of the most common Week 18 fantasy football lineup decisions are regarding players ...

San Francisco 49ers head coach Kyle Shanahan shared the final injury report on QB Brock Purdy, TE George Kittle and others before the team's Week 18 matchup against the Cardinals and shared his vision ...

Isaac Guerendo, RB, SF (foot/hamstring) — Expected to play In Guerendo’s Week 16 absence, Patrick Taylor had eight carries for 24 yards, while WR Deebo Samuel had five carries for 25 yards. But ...

There are numerous player prop betting options on Isaac Guerendo for the 8:15 PM ET game Monday, which airs live on ABC/ESPN.

The Detroit Lions defense struggled, particularly the linebackers and special teams, despite two key interceptions from Kerby Joseph.

SF 49ers coach Kyle Shanahan, quarterback Brock Purdy, lineman Nick Bosa, linebacker Fred Warner speak after loss to Lions ...

San Francisco 49ers head coach Kyle Shanahan recapped the team's 40-34 loss to the Detroit Lions, evaluated the 49ers performance on "Monday Night Football" and shared injury updates on QB Brock Purdy ...

The Detroit Lions will face the San Francisco 49ers in week 17 of the NFL season on Monday Night Football at Levi's Stadium ...

San Francisco 49ers host the Detroit Lions on Monday Night Football to disrupt the Lions' quest for the NFC's No. 1 seed.

The Detroit Lions (13-2) will face off against the San Francisco 49ers (6-9) on Monday, December 30, 2024 at Levi’s Stadium.

The 49ers (6-9) have won so few they are vacating the NFC throne, having been eliminated last Sunday from playoff contention.