Researchers at the Regensburg Center for Biochemistry (RCB) and the Regensburg Center for Ultrafast Nanoscopy (RUN) at the ...

A new study has found that ORC plays a broad, unexpected role in regulating human cell gene expression and chromatin ...

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules.

Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according ...

The six-subunit ORC is essential for the initiation of DNA replication in eukaryotes. Cancer cell lines in culture can survive and replicate DNA replication after genetic inactivation of individual ...

Abstract Mismatch repair (MMR) is a replication-coupled DNA repair mechanism and plays multiple roles at the replication fork. The well-established MMR functions include correcting misincorporated ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified.

John Diffley is a biochemist recognized for his work on eukaryotic DNA replication. He is especially known for his work on the mechanism and regulation of replication initiation. Diffley was born and ...

We explain how to add Distributed File System (DFS) roles, and then configure DFS Namespace and DFS Replication on a Windows Server.