While dopamine-related mechanisms in feeding and obesity have been well-studied, the impact of chronic high-fat diets (HFDs) on inhibitory NAc→VTA projections remains unclear.

In normal-diet mice, this NAc→VTA circuit drives hedonic feeding—the kind of eating that happens not because you're hungry, but because something tastes good.

Some commuters expressed support for the strike despite the inconvenience – as well as a hope that it ends soon.

Pain response and pain-related behavior changes to the artificial manipulation of the VTA glutamatergic projections to NAc were observed by Hargreaves tests, von Frey tests, open field tests, elevated ...

Taken together, we demonstrated that the NAc and the VTA are innervated by two, mostly nonoverlapping mPFC populations with different laminar distribution and molecular profile. These results can ...

Abstract Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement The long-range GABAergic input from the ventral ...

To monitor dopamine neural activities in the ventral tegmental area (VTA) in response to nicotine, we designed a dopamine platform based on a microimaging device and a microdialysis system. We ...