A new study has found that ORC plays a broad, unexpected role in regulating human cell gene expression and chromatin ...

DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of ...

Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules.

At two gene loci the researchers studied, increased looping in the absence of ORC2 isolated a known gene enhancer from the ...

DNA evidence links Travis Decker to murder of 3 daughters Three young sisters were found dead near a Washington state campground. Blood found on the scene links the father, Travis Decker, to those ...

Abstract. Acquiring nucleotides is essential for all dividing cells, and failure to maintain sufficient levels and balance of nucleotides impairs DNA replication. Eukaryotic cells meet nucleotide ...

Abstract Mismatch repair (MMR) is a replication-coupled DNA repair mechanism and plays multiple roles at the replication fork. The well-established MMR functions include correcting misincorporated ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified.

John Diffley is a biochemist recognized for his work on eukaryotic DNA replication. He is especially known for his work on the mechanism and regulation of replication initiation. Diffley was born and ...