Portland Timbers (9-7-7, seventh in the Western Conference) vs. Los Angeles FC (10-5-6, sixth in the Western Conference) ...

LA Galaxy (3-14-7, 16th in the Western Conference) vs. Houston Dynamo (7-11-6, 12th in the Western Conference) ...

Nashville SC (14-5-5, first in the Western Conference) vs. San Diego FC (13-7-4, second in the Western Conference) ...

Orlando City SC (10-6-8, fifth in the Eastern Conference) vs. Columbus Crew (12-4-8, third in the Eastern Conference) ...

CF Montreal (3-15-6, 14th in the Eastern Conference) vs. New England Revolution (6-10-7, 10th in the Eastern Conference) ...