RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which ... ribosomal and small nuclear RNA (tRNA, rRNA, snRNAs) fold into unique structures ...

Is m5C in mRNA only a result of the Star activity of tRNA or rRNA modification enzymes, or is their low stoichiometry biologically relevant? In light of the short-comings of existing tools to robustly ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

CureVac and partner GSK are, meanwhile, also developing an mRNA-based flu vaccine, but are a little further back in development, as their shot is in phase 1 testing.

GSK has upgraded its longstanding alliance with CureVac on mRNA-based vaccines for respiratory infections, paying €400 million ($429 million) upfront for global rights to its influenza and COVID ...

Ninetails, a neural network that uses Nanopore Direct RNA sequencing data to identify non-A residues in mRNA poly(A) tails is presented. Particularly non-A of therapeutic, mitochondrial ...

After hours: March 21 at 7:58:23 PM EDT Loading Chart for MRNA ...

(H) The density map showing the distribution of editing events across the mRNA transcripts detected by DRAM-seq. A comparison of three biological replicates from each experimental group revealed a ...