There wasn’t much to play for when the San Francisco 49ers and Arizona Cardinals suited up Sunday at State Farm Stadium. The ...

Even the officials are not being able to evade Kyle Shanahan's frustration this time. The post Kyle Shanahan Questions NFL ...

Isaac Guerendo speaks to the media after San Francisco's 47-24 loss to the Arizona Cardinals to reflect on his rookie season.49ers Guerendo shares injury concern, reflects on rookie season originally ...

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ ...

Per head coach Kyle Shanahan, San Francisco 49ers running back Isaac Guerendo (knee, ankle) has likely picked up an MCL ...

George Kittle and Kyle Juszczyk said after the Sunday's season-ending loss to Arizona that they hope their futures remain in ...

San Francisco running back Isaac Guerendo exited the 49ers' season finale versus the Arizona Cardinals just four plays into ...

San Francisco 49ers QB Joshua Dobbs and LB Fred Warner reacted to the 49ers season finale against the Arizona Cardinals.

Jauan Jennings' ejection and Isaac Guerendo's cart-off knee injury added to the 49ers' season-long macabre in Sunday's 47-24 ...

San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...

The 49ers fear RB Isaac Guerendo suffered an MCL injury against the Cardinals in Week 18. Kyle Shanahan provides several injury updates from the game.