Some viruses fuse contacting cell plasma membranes, which can contribute to viral spread. Other viruses subvert the host cell cytoskeleton to aid in their cell-to-cell spread. Some viruses travel ...
The spike protein of the coronavirus, or SARS-CoV-2, binds to ACE2, a receptor on the host cells, which allows the virus to enter the cells and infect it. Binding is the first step for infection, and ...
Viruses carry only a limited set of instructions in their own genetic material, so to reproduce they rely on taking over host cell proteins and functions. Shah's laboratory studies these interactions ...
Researchers discover how Zika virus and related viruses replicate in human cells, illuminating potential new vaccines.
The study, published today in the journal Cell Host & Microbe, sheds light on the molecular rules that govern how filoviruses ...
The only natural host of the hepatitis C virus (HCV) is humans. Model organisms for laboratory studies, especially mice, ...
Researchers at the Max Planck Institute of Biophysics and Heidelberg University have observed largely intact HIV-1 capsids as ...
Bacteria are single-celled living organisms capable of thriving independently, whereas viruses are non-living particles that must invade host cells to reproduce. These differences influence how ...
Viruses carry only a limited set of instructions in their own genetic material, so to reproduce they rely on taking over host cell proteins and functions. Shah's laboratory studies these ...
Researchers have profiled the molecular structure and features of a key part of the deadly Nipah virus. Experiments in cells showe how changes in the viral polymerase -- a protein involved in viral ...
Zika virus is unusual in that it can cross the placenta and enter the fetus, where ANKLE2 is known to play a big role in brain development.