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How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...
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Live Science on MSNScientists uncover 'coils' in DNA that form under pressure
Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...
The CGG triplet repeat binding protein 1 counteracts R-loop induced transcription-replication stress
CGGBP1 binds to short CGG repeats in gene promoters, recruiting RNA:DNA helicases like DDX41 to ensure proper transcription ...
Could a natural check on cancer be used to stop the disease? It's possible, but to leverage a system that nature designed, we ...
Hypoxia-inducible factors (HIFs), ETS-1, MYC, and β-catenin act as master regulators that constitutively activate oncogenic ...
DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...
A new AI tool reveals how tangled DNA knots impact health and disease, offering insights for drug discovery and genetic ...
This highlights an important preclinical model that could be successful in humans. The notoriously persistent, ...
During development, many crucial genes help organisms form properly. One of those genes is MyoD | Genetics And Genomics ...
In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...
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