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How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...
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Live Science on MSNScientists uncover 'coils' in DNA that form under pressure
Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...
The CGG triplet repeat binding protein 1 counteracts R-loop induced transcription-replication stress
CGGBP1 binds to short CGG repeats in gene promoters, recruiting RNA:DNA helicases like DDX41 to ensure proper transcription ...
Could a natural check on cancer be used to stop the disease? It's possible, but to leverage a system that nature designed, we ...
Hypoxia-inducible factors (HIFs), ETS-1, MYC, and β-catenin act as master regulators that constitutively activate oncogenic ...
A new AI tool reveals how tangled DNA knots impact health and disease, offering insights for drug discovery and genetic ...
This highlights an important preclinical model that could be successful in humans. The notoriously persistent, ...
DNA Methylation Market OverviewDNA methylation is a biological process in which methyl groups (CH3) are added to the DNA ...
Here, we define a requirement for neural activity in mobilizing the antioxidant defenses of the nematode Caenorhabditis elegans both during chronic oxidative stress and prior to its onset. We show ...
Researchers have uncovered how paraspeckles, which are implicated in cancer, form in the nucleus, challenging the ...
A new study by Dr. Tian Ye's group from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of ...
RNAConnect, a leader in next-generation molecular biology tools, today announced the commercial launch of the UltraMarathonRT ...
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