CGGBP1 binds to short CGG repeats in gene promoters, recruiting RNA:DNA helicases like DDX41 to ensure proper transcription ...

How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

RNAConnect, a leader in next-generation molecular biology tools, today announced the commercial launch of the UltraMarathonRT ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

Hypoxia-inducible factors (HIFs), ETS-1, MYC, and β-catenin act as master regulators that constitutively activate oncogenic ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

Could a natural check on cancer be used to stop the disease? It's possible, but to leverage a system that nature designed, we ...

Researchers have uncovered how paraspeckles, which are implicated in cancer, form in the nucleus, challenging the ...

Here, we define a requirement for neural activity in mobilizing the antioxidant defenses of the nematode Caenorhabditis elegans both during chronic oxidative stress and prior to its onset. We show ...