ELX-02 treatment improved podocyte foot process effacement in all three patients by an average of 60% based on a blinded kidney biopsy analysis by NIPOKA GmbH Biopsy results support clinical ...

Kidney morphology improved in all three patients with protein re-expression consistent with disease regression in its Phase 2 open-label clinical trial of ELX-02 for the treatment of Alport Syndrome.

Cross-sectional images of IgA nephropathy murine kidneys. Purespring gene therapy significantly improves kidney morphology and reduces the areas of scarring and fibrosis stained in blue. Results ...

In a mouse model of IgA nephropathy, mice given PS-002 had lower levels of complement deposited in their kidney cells and less protein in their urine, along with healthier kidney morphology ...

Laboratory Investigation - Genome-wide gene-expression patterns of donor kidney biopsies distinguish primary allograft function Skip to main content Thank you for visiting nature.com.

Zebrafish help investigators shed light on the mechanisms underlying cilia dysfunction in polycystic kidney disease and other ciliopathies. Cilia, the finger-like protrusions on most epithelial ...

Resolvin D-1 limits kidney damage after heart attacks. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2018 / 02 / 180220170402.htm ...

Improvement in kidney morphology drives clinical benefit in this devastating rare disease,” said Sumit Aggarwal, President and Chief Executive Officer of Eloxx.

In a paper published in The FASEB Journal, Halade and colleagues found that resolvin D-1 limits heart attack-induced kidney inflammation in their mouse model, ...

Podocyte Exact Morphology Procedure Results. ELX-02 treatment improved podocyte foot process effacement in all three patients by an average of 60% based on a blinded kidney biopsy analysis by ...