To address these questions, we have characterized the accessibility and TF binding in putative gene regulatory elements and correlated ... Conservation was also calculated for exon and intron regions ...

Using an O-GlcNAc responsive GFP reporter cell line, we identify SFSWAP, a poorly characterized splicing factor, as a trans-acting factor regulating OGT intron detention. We show that SFSWAP is a ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

The sale of bluebird bio and Pfizer’s decision to drop a gene therapy for hemophilia have led to some anxiety regarding the future of cell and gene therapy (CGT). As the chief executive officer ...

Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers from the Institute of ...

The researchers used bioinformatic and mathematical methods to analyze the positions of more than 4,400 gene families in over ...

Gene Hackman and his wife Betsy Arakawa were found dead inside their home surrounded by tragic conditions. The Hollywood legend, 95, and Betsy, 65, were found dead on February 26 at their home in ...

Health officials found extensive evidence of rats on Gene Hackman’s New Mexico property during a hantavirus risk assessment test after the star’s wife was killed by the rodent-linked disease ...

It is thought she died more than a week before her husband. Authorities have released a trove of records related to the deaths of Gene Hackman and his wife, Betsy Arakawa, including a lengthy ...