To create ciliary flow, cilia — hair-like structures that propel mucus out of airways — need to be polarized along the planar axis of the epithelium, but how polarity is established in ciliated ...
Cilia are evolutionarily conserved microtubule-based organelles that function as sensory and motile hubs central to mucosal immunity and systemic immune homeostasis. Motile cilia drive mucociliary ...
The primary cilium is an antenna-like structure of the plasma membrane, which is composed of the basal body, the transition zone, and the axoneme. Primary cilia contain receptors and channels that ...
Primary cilia and planar cell polarity (PCP) proteins both contribute to cell polarization, but their relationship is unclear. A new study shows that, in the organ of Corti, primary cilia are required ...
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