State officials are warning the public to avoid handling birds and other wildlife as suspected avian flu cases are now “widespread” in Massachusetts.

The number of bird flu cases in Central Massachusetts is relatively low, compared to a swath of the state that runs from Greater Boston to Southeastern Massachusetts. That message was delivered Wednesday during a virtual update from state health officials on the highly pathogenic avian influenza H5N1 virus.

Bird flu appears to be widespread in Massachusetts, state health and environmental officials said Wednesday. The Division of Fisheries and Wildlife (MassWildlife), the Massachusetts Department of Agricultural Resources (MDAR) and the Massachusetts Department of Public Health (DPH) said bird flu -- also known as highly pathogenic avian influenza (HPAI) -- is suspected to be the cause of death in cases of both wild and domestic birds in several Massachusetts municipalities.