Recombinant DNASE1L3 therapy reduced symptoms in a patient with severe lupus with DNASE1L3 deficiency. Antidrug antibodies caused effects to wane, but findings support NET-targeted therapy as a ...

A patient with type 1 diabetes received genetically modified allogeneic islets and no immunosuppression. Results obtained ...

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 3).

Aspirin after an initial short course of rivaroxaban has been shown to be safe and effective for the prevention of venous thromboembolism after total hip or total knee arthroplasty, but uncertainty ...

Explore this issue of The New England Journal of Medicine (Vol. 389 No. 26).

Explore this issue of The New England Journal of Medicine (Vol. 395 No. 2).

Caring for undocumented immigrants at a time of heightened fear requires actionable frameworks guided by compassion and respect. Trauma-informed care is a vital approach for physicians.

Growing acceptance of voluntary euthanasia, which opens the door to death by organ donation, warrants a recontextualization of the dead donor rule and assessment of the ethical principles involved.

Ashish Verma can be contacted at [email protected]. Supported by an American Heart Association Career Development Award (24CDA1274501) and a Boston University Chobanian and Avedisian School of ...

To the Editor: In the Study of Tirzepatide Compared with Dulaglutide on Major Cardiovascular Events in Participants with Type 2 Diabetes (SURPASS-CVOT), Nicholls et al. (Dec. 18/25 issue)1 found th ...