Quality control (QC) is vital to the in vitro transcription (IVT) RNA workflow. Because IVT RNA synthesis generates RNA that scientists use in multiple downstream applications, it is critical to start ...

More information: Tanja Bhuiyan et al, TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicing factors, Cell Reports (2025). DOI: 10.1016/j.celrep.2025.115616 ...

Transcription comprises a template-switching during the subgenomic negative-strand RNA synthesis to incorporate a replica of the leader sequence into the developing negative RNA.

Abstract Unlocking the potential of mRNA technology is helping revolutionize medicine and biotechnology. Solid-phase in vitro transcription enables scalability and automation, helping make it a ...

A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural ...

CGGBP1 binds to short CGG repeats in gene promoters, recruiting RNA:DNA helicases like DDX41 to ensure proper transcription ...

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

GenScript continues to build on its fast and dependable in vitro transcription RNA synthesis service, offering a new self-amplifying RNA format that enhances the potency and efficacy of vaccines ...

Proteins that bind DNA or RNA are usually put in different categories, but researchers at Umeå University in Sweden and Inserm in France recently showed how the p53 protein has the capacity to ...

Bhuiyan et al. TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicing factors. Cell Reports, Vol. 44, Issue 5, 2025. DOI: 10.1016/j.celrep.2025.115616 Contact ...