RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions ...

RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions ...

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

Researchers at San Diego State University and Michigan State University are shedding new light on how viruses meticulously ...

Yale researchers have developed a new and safe family of RNA-editing tools that utilize an RNA-targeting activity that they ...

Similar to the way the caps on the ends of a shoelace prevent it from fraying, telomeres—regions of repetitive DNA sequences ...

And then there’s the paucity of known RNA structures. The Protein Data Bank, a repository of 3D macromolecular structures, contains nearly 200,000 protein structures and fewer than 2,000 RNAs.

Using this time scale, the structures of many life saving RNA may not be discovered for years. As a result, there is a significant gap between the types of known RNA and the available structural data.

The image on the laptop screen shows the 3D structure of a large protein-free RNA complex — one of three unprecedented structures their research collaboration discovered using cryo-EM at SLAC.

By modeling RNA's 3D structure, we can help bridge the gap created by the lack of experimentally determined structures, advancing research on RNA and its crucial roles in life and health.” “It took ...