In 1961 the structure of one protein, myoglobin ... Why should fast kinetics provide evidence for folding intermediates when equilibrium tests showed only two-state folding?

Understanding the physical basis for this activity requires knowledge of the equilibrium and kinetic ... such as the folding of regions of a protein around a prosthetic group, or from changes ...

"Now that we know the properties of protein cores under typical folding conditions, it's possible that protein core packing does not need to stop at 55%," said Alex Grigas, a Ph.D. candidate in O ...

(a) A two-state transition independent of protein concentration ... by agitation, the folding/unfolding transition and the aggregation to polymeric states (P) enter an equilibrium, and the ...