Physiologically based pharmacokinetic (PBPK) modeling integrates knowledge of physiology and biochemistry to describe the biological processes that regulate chemical uptake, distribution, metabolism, ...
Blood samples for pharmacokinetic analysis were collected prior to the initiation of patient dosing, and, at 10, 20, and 40 minutes after patient dosing, as well as at 1, 3, 6, 24, 48, 72, and 144 ...
PhysPK stands as a flexible and robust bio-simulation and modeling software designed for analysis of population pharmacokinetics (PK) and pharmacodynamics (PD) systems. PhysPK equips users with ...
EDINBURGH, Scotland, Dec. 11, 2024 /PRNewswire/ -- TC BioPharm (Holdings) PLC ("TC BioPharm" or the "Company") (NASDAQ: TCBP) a clinical-stage biotechnology company developing platform allogeneic ...
Background: A physiologically based pharmacokinetic (PBPK) model would make it possible to simulate the dynamics of chemical absorption, distribution, metabolism, and elimination (ADME) from different ...
Randomized Trial of Procarbazine, Lomustine, and Vincristine in the Adjuvant Treatment of High-Grade Astrocytoma: A Medical Research Council Trial PURPOSE: To determine the recommended dose, toxicity ...
The disposition kinetics of enrofloxacin at a single dose of 5 mg/kg body weight were determined in clinically healthy captive-reared estuarine crocodiles (Crocodylus porosus) after intravenous (i.v.) ...
The two-compartment pharmacokinetic model described the mechanisms how human body handles with ingestion of NC-cyclodextrin complexes in gastrointestinal tract (GI), distribution in the blood (Plasma) ...
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