RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions ...

The structure and chemistry of nucleic acids is fundamental to their function, from the DNA double helix discovered by Watson and Crick to the intricate secondary and tertiary structures adopted by ...

Characterizing the interactions between nucleic acids and host proteins or other molecules is also critical to understanding the underlying biology of both healthy and disease states.

Review Article Published: 22 June 2012 Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination Christophe J. Desmet & Ken J. Ishii Nature Reviews Immunology 12 ...

The Nucleic Acids Institute is dedicated to uncovering the chemical and biological underpinnings of nucleic acid function, and to developing innovative nucleic acid-based therapies and applications.

Abstract Nature encodes nucleic acids to assemble enormously complex and highly functional materials that form the foundation of life. To establish a similar code to construct synthetic, unnatural ...