DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural ...

Scientists at the Guangzhou Institutes of Biomedicine and Health, part of the Chinese Academy of Sciences in Guangzhou, China ...

“We’re thrilled to have had the opportunity to work with TriLink on the launch of CleanScribe RNA Polymerase,” shared Chad Decker, VP and General Manager at Alphazyme.

In the Herman Lab, we set out to exploit the speed and power of bacterial genetics to understand the interactions between transcription, core transcription factors, and genome maintenance.

Investigators may have uncovered the general mechanism that governs RNA polymerase movement, they report in the January 28 issue of Cell. The finding "provides a framework for understanding how ...

This is where DNA and RNA epigenetics comes in: a series of mechanisms that act as "markers" on genes, to control their activity without modifying the DNA or RNA sequence itself.

A recent study in Nature Communications examined how RNA polymerase I (Pol I) responds to abasic (Ap) site formation—the most common type of DNA damage. The researchers found that Pol I helps ...