Scientists revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement ...

Neural crest cells have been thought to originate in the ectoderm, the outermost of the three germ layers formed in the earliest stages of embryonic development. But their capacity to form derivatives ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Reviewed by Michael Greenwood, M.Sc. Fertilization is defined as a process where gametes (an egg and sperm) join together to form a full zygote. Both the sperm and egg contain a single set of 23 ...

When the zygote, or the fertilised egg, starts to develop, the soon forming inner cell mass, a cluster of cells that will eventually develop into the individual, retains its pluripotent stem cell ...

Embryonic germ layers are the fundamental organizing principle in animal development. They provide the structural basis from which tissues and organs arise. During early embryogenesis, cells divide to ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...

Huntington’s disease (HD) was the first neurological disorder to be linked to a mutation in a single gene—a discovery made more than 25 years ago. However, neither the pathogenic mechanisms leading to ...

Subscribe to our newsletter for the latest sci-tech news updates. The work appears in Cell. "Understanding embryo implantation and embryo development just after implantation has significant clinical ...