DNA- and RNA-binding proteins (DRBPs) constitute a significant fraction of cellular proteins and have important roles in cells. Their functions include control of transcription and translation, DNA ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

Histone proteins at the core of nucleosomes and their tails exert control over the exposure of genes for binding, as demonstrated in simulations researchers. The protein complex that holds strands of ...

Biologists were puzzled by the discovery of left-handed Z-DNA because it seemed unnecessary. Z-DNA was stabilized by the negative supercoiling generated by transcription, which indicated a transient ...

Supercoiling and looping can transmit mechanical stress along the DNA backbone that can promote the separation of the strands of the double helix at specific distant sites, exposing the DNA bases, ...

A region of DNA that codes for a protein, often referred to as a gene, is the fundamental unit of heredity responsible for specific traits and functions within an organism. This intricate segment of ...

Neuroscientists have uncovered a new mechanism for memory formation, and it involves changes in the structure of your DNA. If you were asked to picture a molecule of DNA, chances are you would ...

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...