Hosted on MSN
Genetic model reveals a form of calcium release is unnecessary for normal muscle contraction
The research team developed a genetically engineered mouse model carrying a mutation (E3896A) in RyR1, which disrupts its calcium-binding site, effectively disabling CICR while preserving ...
Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people.
Some results have been hidden because they may be inaccessible to you
Show inaccessible results