Measuring the tRNA world Researchers have developed a method to quantify transfer RNAs Date: February 26, 2021 Source: Max-Planck-Gesellschaft Summary: Transfer RNAs (tRNAs) deliver specific amino ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction ...

A promising new study has identified a highly accurate, non-invasive method to diagnose non-small cell lung cancer (NSCLC) ...

Alltrna’s thesis is that one tRNA could be used to treat “thousands of diseases,” as Lovisa Afzelius, an origination partner at Flagship and co-founding CEO of Alltrna, told TechCrunch.

This publicly traded San Diego-based biotherapeutics company has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA ...

A tRNA splicing endonuclease catalyzes dual incisions of the pre-tRNA at the exon-intron borders to yield 2’,3’-cyclic-PO 4 and 5’-OH termini. The joining phase of tRNA splicing has been characterized ...

The initiator tRNA which is equipped with the anticodon (UAC) also binds to the start codon (AUG) of the mRNA. The resulting large complex forms a complete ribosome and initiates protein synthesis.

Alltrna, the preclinical Flagship Pioneering-backed biotech trying to turn transfer RNA (tRNA) into drugs, is slimming down as it works toward the clinic. The Massachusetts-based outfit has laid ...