The detection limit of the array hybridization was found to be 50 pg, corresponding 0.01% of the total poly (A) + RNA. cDNA array hybridization was linear from 50 pg to 1,000 pg.

Myriam Hemberger, James C. Cross, Hans-Hilger Ropers, Hans Lehrach, Reinald Fundele, Heinz Himmelbauer, UniGene cDNA Array-Based Monitoring of Transcriptome Changes during Mouse Placental Development, ...

cDNA array data, as well as real-time RT-PCR data (control versus clozapine treatment), were analyzed by Student's t -test. An expression change was considered significant at P <0.05.

Stephan Brandt, Sebastian Kloska, Thomas Altmann, Julia Kehr, Using array hybridization to monitor gene expression at the single cell level, Journal of Experimental Botany, Vol. 53, No. 379 (December ...

Tumor tissue was collected and snap-frozen from 35 sequential patients with histologically confirmed LPC being treated with CRT. Gene expression analysis was performed using a novel cDNA array ...

Breast cancer is one of the most common cancers in the world. Triple-negative breast cancer (TNBC) is a sub-type of breast cancer characterized by its appearance in younger women and its relative ...

In terms of molecular diagnosis, protein arrays have also been used to identify signatures that discriminate between pancreatic cancer patients and healthy subjects. [59, 60] The use of antibody ...

Core biopsies from 24 patients were obtained before treatment with neoadjuvant docetaxel (four cycles, 100 mg/m 2 every 3 weeks), and response was assessed after chemotherapy. After 3 months of ...

Biomarkers for Progression & Survival in Pancreatic Cancer Another interesting goal of gene-expression profiling has been the search for gene predictors of a better prognosis. Pancreatic cancers ...