G protein-coupled receptors (GPCRs) are the largest and most diverse group of cell surface proteins in humans. These receptors, which can be seen as "traffic directors," transmit signals from the ...

To fill in the blanks on mitochondria, researchers deleted 174 genes, one by one, in yeast. They then subjected the yeast to high-intensity mass spectrometry to measure unprecedented detail on ...

A research team from Whitehead Institute has uncovered a surprising and previously unrecognized role for introns, the parts of genes that lack the instructions for making proteins and are typically ...

“No one has carried out an evolutionary study of this kind before and certainly not of this scale,” said Nevan Krogan of the University of California, San Francisco, who was not involved in the work. ...

Zachary Gergely, Ammon Crapo, Loren Hough, J. Richard McIntosh, and Meredith D. Betterton (2016). Molecular Biology of the Cell27, 3490. arXiv DOI: 1604.08134. DOI ...

Researchers have revived living yeast from the preserved remains of Ötzi the Iceman, a 5,300-year-old mummy discovered in the Alps. The cold-adapted strain, extracted from his gut and surrounding ...

Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into ...

The proposed approach involves causing random mutations on human derived receptor H 3 R and introducing the altered genetic code into yeast cultures. This allows for the convenient screening of ...