Splice plates are flat steel plates used to join and strengthen the beam joints, especially critical in a steel splice to ensure structural integrity High-strength bolts and nuts help fasten beams ...

Splicing of pre-messenger RNA is regulated differently in the brain compared with other tissues. Recognition of aberrations in splicing events that are associated with neurological disease has ...

Incorrect splicing can result in disease due to mutations in a gene that affect pre-mRNA features important for splicing, mutations in genes coding for components or regulators of the spliceosome ...

Dubbed the ‘guardian of the genome’, the p53 protein responds to DNA damage by stalling cell division, initiating DNA repair ...

Splicing is closely linked with transcription, involving a dynamic interaction between the mRNA, RNA polymerase II (Pol II), and chromatin structures. 5 “There's strong evidence that splicing of ...

Stopping Metastasis by Blocking the Site of Deviant RNA Splicing To treat metastatic breast cancer, the study authors suggested, it may be possible to target the RNA splice site that generates the ...

Splicing factor mutations are particularly prevalent in MDS, a group of heterogeneous hematological disorders characterized by defective blood stem cells and a high risk of leukemia development.