ATLANTA -- The concept of using stents to seal off non-flow-limiting vulnerable plaques, before they have a chance to rupture, worked out in the first major trial testing this provocative idea.

The 'vulnerable' plaque is a term which describes a plaque that is destabilized and thus prone to induce atherosclerotic cardiovascular events. The determination of biomarkers related to ...

The final stage of atheroma progression is characterized by a large necrotic core and low SMC density, with a correspondingly thin fibrous cap — a vulnerable plaque prone to rupture and thrombosis.

Studies with darapladib in humans are now underway, and it remains to be established whether Lp-PLA 2 inhibition can also reduce the formation of vulnerable plaques in humans, and, ultimately ...

Some atherosclerotic plaques have a stable fibrous cap; others, with a thin cap, are considered “vulnerable.” Unfortunately, only a few research centers have access to the techniques and ...

Detecting vulnerable plaques is now possible using the latest intravascular imaging technology. We focus on how this can help with early detection of heart disease and prevention of its recurrence.

[26] In addition, some of the changes in circulating marker levels may be a consequence of silent plaque rupture and/or subsequent healing. Detection of vulnerable or rupture-prone lesions is of ...