Scientists have found a way to map the intricate patterns of cells in mouse brain tissue with an off-the-shelf light microscope, using a trick that inflates a tiny sample to 16 times its original size ...

A technique that supersizes cells to reveal minute details has gone big — really big. Using a polymer similar to those used in nappies to make them super-absorbent, scientists have expanded the volume ...

With a new microscope that's as light as a penny, researchers can now observe broad swaths of the brain in action as mice move about and interact with their environments. As a mouse explores its ...

Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to enable improved optical sectioning over a larger area of view. The advance makes the technique more ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

Modern microscopes opened up the world of the minute to an amazing degree, allowing people to see all the way down to a bacterium wriggling on a slide. But if you want to see down even smaller in ...

Researchers at the University of Illinois at Urbana-Champaign have shown for the first time that expensive aberration-corrected microscopes are no longer required to achieve record-breaking ...

What is the Diffraction Limit? The diffraction limit is a fundamental barrier in optical microscopy that sets the minimum size of features that can be resolved using conventional light microscopes. It ...