Cancer cells that slip free of chemotherapy’s deadly embrace sometimes manage to do so because they possess slippery DNA repair proteins. Among the slipperiest are translesion synthesis (TLS) ...
Correlation between HER2 amplification level and response to neoadjuvant treatment with trastuzumab and chemotherapy in HER2 positive breast cancer. ER+ breast cancer response to NACT response and ...
Mutations in oncogenes and tumor suppressor genes are critical in the development of cancer. A major pathway for the formation of mutations is the replication of unrepaired DNA lesions. To better ...