How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

SMRTS, a smart mRNA system, enables cell‑selective gene expression, expanding the mRNA toolbox for precision cancer therapies.

LNP as the novel drug delivery system enhancing mRNA therapeutic efficacy has been proved for its delivery ability. This review provides valuable insights into the current state-of-the-art of LNP mRNA ...

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...

In recent years, mRNA technology enabled the rapid development of vaccines to fight COVID-19, saving millions of lives. That same mRNA-powered approach to medicine—in which synthetic mRNA is ...

Vaccines have been reliably and affordably protecting people from diseases worldwide for centuries. Until the COVID-19 pandemic, however, vaccine development was still a long and idiosyncratic process ...

Vaccines that resemble viruses generally produce a stronger immune response, while mRNA versions are much quicker and cheaper to make. Now we are getting the best of both worlds, in the form of mRNA ...

The U.S. Department of Health and Human Services (HHS) recently announced it will wind down funding for mRNA vaccine development—which could prove to be one of the costliest, deadliest decisions HHS ...

mRNA vaccines train the immune system in a similar way to traditional vaccines, but they use a different strategy to get there. When you purchase through links on our site, we may earn an affiliate ...