A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural ...

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

This is where RNA —messenger RNA (mRNA), to be exact— comes into play. Whereas DNA is used for long-term storage, mRNA acts as a shuttle of single-use genetic instructions.

Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

Aug 12, 2025 Pressing pause on DNA transcription What happens on the atomic scale when DNA transcription is paused has been unveiled for the first time. (Nanowerk News) A detailed picture of what ...

Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

All living things rely on RNAP to transcribe DNA into RNA. In bacteria, researchers have long known that transcription begins when RNAP clamps onto a DNA strand and initiates the process after ...

More information: Guowu Lin et al, Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser, Proceedings of the National Academy of ...