Hypoxia-inducible factors (HIFs), ETS-1, MYC, and β-catenin act as master regulators that constitutively activate oncogenic ...

Jie Dong, Ning Sun, Jing Yang, Zhaoguo Deng, Jingqiu Lan, Genji Qin, Hang He, Xing Wang Deng, Vivian F. Irish, Haodong Chen, Ning Wei, The Transcription Factors TCP4 and PIF3 Antagonistically Regulate ...

For years, scientists have considered transcription factors to be undruggable, but new research published this month in Molecular Cell shows they may be druggable after all (2024, DOI: 10.1016/j ...

Researchers genetically reprogrammed mouse nerve cells to reverse cell aging, delaying the onset of ALS symptoms in the animals.

Researchers mapped 408 genes linked to frailty, revealing distinct biological aging patterns and possible personalized care ...

For more than 30 years, scientists have studied how the myogenic determination gene number 1 (MYOD) protein binds DNA to ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report ...

A new study by Dr. Tian Ye's group from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of ...

Computational research in fruit flies revealed how spontaneously arising genes are tightly controlled, offering insights into ...

A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural ...