A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural ...

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

Transcription factors can increase and decrease gene expression, and sometimes work with protein partners to do so; they tend to have an end that can bind to DNA and another end that can attach to ...

During transcription, the first step in gene expression, RNAPs "read" DNA sequences and assemble messenger RNA (mRNA), which in turn serves as the template for the proteins necessary for life.

How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

Proteins are produced from RNA (ribonucleic acid). But our genes are stored in the form of DNA. So, this DNA first needs to be converted into RNA. In technical lingo, this is called transcription.

Dr. Young and lead authors Ozgur Oksuz, Ph.D., and Jonathan E. Henninger, Ph.D., and colleagues discovered that at least half of the approximately 1,600 TFs in the human genome also bind to RNA.

Click chemistry–based RNA sequencing captures bursts of transcription A new technique allows scientists to track RNA expression in single cells at the moment genes are transcribed from DNA to RNA.

Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.