Figure 1: The structure of the NmM982-TbpB–human transferrin complex. Figure 2: TbpB stabilizes the holo form of human transferrin. The structural data presented here provide the basis for transferrin ...
Bacteria, like all living things, need iron for a variety of biochemical functions. Humans and other higher order organisms have plenty of iron; we limit bacterial access to it as a means of defending ...
(SALT LAKE CITY) – Examination of DNA from 21 primate species – from squirrel monkeys to humans – exposes an evolutionary war against infectious bacteria over iron that circulates in the bloodstream.
Scientists from the University of Utah examined DNA from 21 primate species and found evidence of an evolutionary war against infectious bacteria over iron that circulates in the host's bloodstream.
Disease is an act of piracy. When microbes infect us, they steal our resources so they can thrive at our expense. We fight them off with direct attacks, using an army of immune cells and antibodies.
A study of primate and bacterial proteins involved in capturing iron from the blood has revealed an evolutionary arms race in the battle over this important nutrient. Matthew Barber and Nels Elde at ...