Researchers at San Diego State University and Michigan State University are shedding new light on how viruses meticulously ...

Like DNA, each RNA strand has the same basic structure, composed of nitrogenous bases covalently bound to a sugar-phosphate backbone (Figure 1). However, unlike DNA, RNA is usually a single ...

The 1.9 Å resolution crystal structure of hepatitis C virus (HCV) nonstructural protein 5B (NS5B) presented here provides the first complete and detailed view of an RNA-dependent RNA polymerase.

In the work, Guo and researchers explored the unique structure of the DNA packaging motor of bacteriophage phi29, a virus that infects bacteria.

Cytosine is one of the four main nitrogenous bases found in DNA and RNA, along with adenine (A), guanine (G), and thymine (T) or uracil (U). It is a pyrimidine derivative, meaning it has a single-ring ...

The most common type of base pairing is the Watson-Crick base pair, named after James Watson and Francis Crick, who first proposed the double helix structure of DNA. In this type of pairing, adenine ...

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing) and under ...

The virus has one of the largest RNA genomes on record and is only the second nidovirus found in bivalves. Nidoviruses are found in a wide range of animals, including humans; for example, SARS-CoV ...