RNA splicing ribozymes have been shown to possess a conserved active site that can engage small molecules, opening possibilities for the control of gene expression.

Chemists at University College London have shown how two of biology's most fundamental ingredients, RNA (ribonucleic acid) ...

Applying ROCK to the Azoarcus intron RNA and the FMN riboswitch, the team managed to identify the different conformations that the Azoarcus intron transitions through during its self-splicing ...

Wang’s lab is focusing on RNA splicing. The processes of transcription, splicing, and translation work together to dictate the amount and composition of proteins, which are drastically different ...

Messenger RNA (mRNA) vaccines have been crucial to containing and controlling the ongoing Covid-19 pandemic. Advances in self-amplifying RNA technology promise to make them even more cost ...

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that ...

Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell ...

A growing body of evidence supports aberrant splicing as both a cause and a potential Achilles’ heel of cancers, especially when it comes to the effects of immune-checkpoint inhibitors.