As aging progresses, the quality of DNA and proteins inside cells declines, which is known to be the cause of various ...

Trans‐translation: A ribosome rescue mechanism in which tmRNA, in complex with SmpB, adds a degradation tag to incomplete polypeptides while freeing stalled ribosomes.

Our cells produce a variety of proteins, each with a specific role that, in many cases, means that they need to be in a ...

Myristoylation is a co-translational process catalyzed by N-myristoyltransferases (NMTs) on ribosomes, but its mechanism ...

They observed comparable defects in ribosome biogenesis in VIRMA-depleted cancer cells, suggesting a potential conservation of this regulatory mechanism across cell types.

Research by UC Santa Cruz molecular biologist Harry Noller and his collaborators has led to the first direct observations of the mechanism for protein synthesis in living cells. Their new findings on ...

When ribosomes go rogue Unusual variations in the cellular protein factory can skew development, help cancer spread, and more. But ribosome variety may also play biological roles, scientists say.

The process of translation by ribosomes, which functions as a factory of protein synthesis, may be impeded by 'ribosome arrest peptides' (RAPs). However, underlying mechanisms remain elusive.

In an article published in Nature Communications, researchers from Uppsala Antibiotic Center, Uppsala University and SciLifeLab describe a fundamental mechanism of antibiotic resistance. What ...

KAIST (President Kwang Hyung Lee) announced that a joint research team—led by Professor Seung-Jae V. Lee of the Department of ...