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In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...
DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...
He zeroed in on Tetrahymena thermophila, a single-celled organism with an unusual genome. Each Tetrahymena carries thousands of copies of the gene for ribosomal RNA, a molecule that builds proteins.
Ribosomal RNA genes are essential for building ribosomes, the machineries that translate proteins. Ribosome biogenesis has long been known as a hallmark of cancer.
Researchers have identified the RNA isoform RUNX1C, which drives chemoresistance in acute myeloid leukemia (AML). The study, ...
Sequencing the glycoRNA molecules turned up hits for ribosomal RNA, transfer RNA, and small nucleolar RNAs, suggesting that they may be repurposed fragments of noncoding nucleic acids. Yet the rules ...
The Rice team's new method, called RNA-addressable modification (RAM), bypasses these hurdles by using a synthetic catalytic RNA (cat-RNA) to "barcode" ribosomal RNA (rRNA) inside living cells.
These fragments showed strong sequence complementarity to ribosomal RNA and a leucine tRNA-derived fragment essential for protein translation (LeuCAG3′-tRF).
Korean scientists may have uncovered a missing link in the biology of aging, potentially opening up a new horizon for unlocking the secret to prolonged youth.