A new technique known as ribose-seq has been developed and tested by researchers. It allows them to determine the full profile of ribonucleotides -- RNA fragments -- embedded in genomic DNA.
Poly(ADP-ribose) polymerase 1 (PARP1) was the first member of the PARP family to be identified. The PARP family now comprises 18 members. PARP1 post-translationally modifies itself and a range of ...
Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study The DNA damage response (DDR) ...
Poly(ADP-ribosyl)ation by poly(ADP-ribose) polymerases regulates the interaction of many DNA damage and repair factors with sites of DNA strand lesions. The interaction of these factors with poly (ADP ...
Many proteins that respond to DNA damage are recruited to DNA lesions. We used a proteomics approach that coupled isotopic labeling with chromatin fractionation and mass spectrometry to uncover ...
In living organisms today, complex molecules like RNA and DNA are constructed with the help of enzymes. So how did these molecules form before life (and enzymes) existed? Why did some molecules end up ...
The sugar ribose is more quickly phosphorylated compared to other sugars with the same chemical formula but a different shape. This selective phosphorylation could explain how ribose became the sugar ...
New research suggests that the sugar ribose -- the “R” in RNA -- is probably found in comets and asteroids that zip through the solar system and may be more abundant throughout the universe than was ...
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