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DENVER — SARS-CoV-2 antigens persist in patients with COVID-19 for months to years after infection, according to data presented at the Conference on Retroviruses and Opportunistic Infections.
A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host ...
To conceptualize this transformation, let's examine the replication of retroviruses, the family of viruses to which HIV belongs. Retroviruses have a single-stranded RNA genome.
BACKGROUND: Endogenous retroviruses (ERVs) occupy >8% of the human genome. Aberrant resurgence of ERVs has been implicated recently in several critical pathologies. However, the possible incidence and ...
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New insights into retrovirus encapsidation mechanisms
To achieve this, Gag binds to a region of the genomic RNA that, depending on the retrovirus, is about 100 to 300 nucleotides long and contains encapsidation signals.
Single-cell RNA analysis of BTBR/R mice revealed changes in the expression of various genes (including stress response genes) that are indicative of endogenous retrovirus activation.
Researchers report February 15 in the journal Cell that ancient viruses may be to thank for myelin—and, by extension, our large, complex brains. The team found that a retrovirus-derived ...
Endogenous retroviruses originate from ancestral retroviral infections where viral RNA was reverse-transcribed into DNA and integrated into the host's germline DNA, thus becoming a heritable part ...
The complex retroviruses, such as HIV, encode additional trans -regulating factors or contain cis -regulating elements, thereby influencing the type and amount of transcribed RNA.
That study reported that the RNA virus called lymphocytic choriomeningitis virus (LCMV) had somehow integrated into the mouse genome -- surprising because with the exception of retroviruses like HIV, ...
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