In eukaryotes, the cell cycle consists of four discrete phases: G 1, S, G 2, and M. The S or synthesis phase is when DNA replication occurs, and the M or mitosis phase is when the cell actually ...

Eukaryotic cells possess an enzyme complex that has RNA polymerase activity, but works in DNA replication. This unique enzyme complex is called DNA primase.

DNA replication and replication stress In eukaryotes, DNA replication initiates at many replication origins that are distributed along the length of each chromosome arm. At each origin, two ...

More information: Bruce Stillman et al, Mechanisms for licensing origins of DNA replication in eukaryotic cells, Nature Structural & Molecular Biology (2025). DOI: 10.1038/s41594-025-01587-5 ...

Mismatch Repair, But Not Heteroduplex Rejection, Is Temporally Coupled to DNA Replication. Science, 2011; 334 (6063): 1713 DOI: 10.1126/science.1210770 ...

Our lab studies the mechanism of eukaryotic chromosome replication. Chromosomes are the carriers of the genetic and epigenetic information and faithful chromosome replication is of fundamental ...

Core DNA replication proteins mediate the initiation, elongation, and Okazaki fragment maturation functions of DNA replication. Although this process is generally conserved in eukaryotes, important ...

BIOL.1220 — Online and Continuing Education Id: 038070 Offering: 2 Credits: 3-3 Description Develops a basic understanding of biological topics relevant to students in the health sciences. Course will ...