The foundation of life lies in the precise replication, transcription and translation of DNA but knowledge about the mechanisms that control the accuracy of transcription remains limited.

This suggests that the absence of TEFM disrupts the proper balance between the replication and transcription processes, which has consequences on mtDNA maintenance and expression.

The RdRp is responsible for a number of functions including 5’cap recognition, endonuclease activity, replication, transcription, and polyadenylation. Recently, cryo-EM reconstitution studies ...

A new study sheds light on one of the roles SARS-CoV-2 NSP13 (nonstructural protein 13) plays in the virus' initial attack on the immune system, which is to degrade a kinase enzyme upstream of ...