Gene editing is a powerful method for both research and therapy. Since the advent of the Nobel Prize-winning CRISPR/Cas9 technology, a quick and accurate tool for genome editing discovered in 2012, ...
Targeted DNA editing by CRISPR technology has great potential for applications in biotechnology and gene therapy. However, precise gene editing remains a challenge largely due to insufficient control ...
Cas9 introduces a DNA double-strand break in the target gene, allowing the gene to be edited when a repair template is present. A drawback to the CRISPR/Cas9 system is that the cellular DNA repair ...
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